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Lkt Laboratories CAS 88899-55-2, ≥90%, Vacuolar H+ ATPase inhibitor. It suppresses autophagy, prevents tumor growth in breast cancer models, and inhibits growth of Plasmodium.
Supplier: Lkt Laboratories B0025
Bafilomycin A1 is a macrolide antibiotic initially produced by Streptomyces that exhibits anti-parasitic, antimalarial, and anticancer chemotherapeutic activities. Bafilomycin A1 inhibits the vacuolar H+ ATPase and suppresses autophagy. Bafilomycin kills Plasmodium parasites in cellular models, and separately, induces cell death and suppresses tumor growth in animal models of breast cancer.
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