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Research Products International Corp Bafilomycin B1, 1 MG
Supplier: Research Products International Corp B521000.001
Bafilomycin B1 is a naturally occurring macrolide antibiotic that is produced by certain strains of Streptomyces bacteria. It is a derivative of bafilomycin, a compound known for its inhibitory effects on the vacuolar-type H+-ATPase (V-ATPase) enzyme.
Similar to other members of the bafilomycin family, Bafilomycin B1 has gained attention in the field of life sciences for its ability to selectively inhibit V-ATPase. This enzyme is responsible for maintaining the acidic pH in various cellular compartments, including lysosomes and endosomes. By inhibiting V-ATPase, it disrupts the acidification process within these compartments. This disruption can have profound effects on various cellular processes and pathways that rely on proper pH regulation, such as protein degradation, autophagy, and vesicular trafficking.
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