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AdipoGen Bafilomycin B1
Supplier: AdipoGen BVT0004C100
Chemical. CAS 88899-56-3. Formula C44H65NO13. MW 815.9. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic. Specific vacuolar-type H-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial compound. Phytotoxic. Influences the cell wall biosynthesis of Asp. niger.
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