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Apexbio Technology LLC Bafilomycin D 98813-13-9 5mg
Supplier: Apexbio Technology LLC C43755
Bafilomycin D is an inhibitor targeting vacuolar-type H -ATPases (V-ATPases) displaying approximate IC of 2 nM in assays utilizing Neurospora crassa-derived enzymes V-ATPases function as proton pumps actively transporting protons across cellular membranes through ATP hydrolysis thus controlling pH homeostasis within intracellular compartments By selectively disrupting proton gradient formation mediated by V-ATPases Bafilomycin D serves as a useful investigative tool in studies of intracellular vesicular trafficking lysosome acidification endocytosis and related membrane transportation mechanisms in biomedical research contexts
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