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Cayman Chemical BAM-22Phumnmouseratb 5mg
Supplier: Cayman Chemical 367235 MG
An endogenous neuropeptide derived from proenkephalin A; expressed in the adrenal medulla and at lower concentrations throughout the brain; binds the µ-, κ-, and δ-opioid receptors (Kis = 0.9, 2.9, and 7.2 nM, respectively); intracerebroventricular administration induces analgesia in a tail-flick assay in mice (ED50 = 6.4 nM); decreases the frequency of tail flicking, as well as paw lifting and licking in a rat model of formalin-induced nocifensive behavior at 5 nM/animal
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