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Apexbio Technology LLC BAMB-4 891025-25-5 5mg
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Catalog No. 502240097
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BAMB-4 (CAS 891025-25-5) is a cell-permeable inhibitor of inositol-1 4 5-trisphosphate 3-kinase A (ITPKA) exhibiting an IC50 of 20 M ITPKA regulates actin filament dynamics and inositol phosphate signaling pathways by binding to and bundling actin filaments BAMB-4 is efficiently taken up by H1299 cells and demonstrates high specificity displaying inhibitory activity with increased Km and reduced Vmax for both InsP3 and ATP indicative of a mixed-type inhibition mechanism Among 42 kinases tested BAMB-4 selectively inhibited ITPKA This compound serves as a valuable tool for studying ITPKA-mediated signaling in cellular models

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Catalog No. 50-224-0097 Supplier Apexbio Technology LLC Supplier No. B47155
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BAMB-4 (CAS 891025-25-5) is a cell-permeable inhibitor of inositol-1 4 5-trisphosphate 3-kinase A (ITPKA) exhibiting an IC50 of 20 M ITPKA regulates actin filament dynamics and inositol phosphate signaling pathways by binding to and bundling actin filaments BAMB-4 is efficiently taken up by H1299 cells and demonstrates high specificity displaying inhibitory activity with increased Km and reduced Vmax for both InsP3 and ATP indicative of a mixed-type inhibition mechanism Among 42 kinases tested BAMB-4 selectively inhibited ITPKA This compound serves as a valuable tool for studying ITPKA-mediated signaling in cellular models

This item is not returnable. View return policy
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