Learn More
Apexbio Technology LLC BAMB-4 891025-25-5 5mg

Supplier: Apexbio Technology LLC B47155
BAMB-4 (CAS 891025-25-5) is a cell-permeable inhibitor of inositol-1 4 5-trisphosphate 3-kinase A (ITPKA) exhibiting an IC50 of 20 M ITPKA regulates actin filament dynamics and inositol phosphate signaling pathways by binding to and bundling actin filaments BAMB-4 is efficiently taken up by H1299 cells and demonstrates high specificity displaying inhibitory activity with increased Km and reduced Vmax for both InsP3 and ATP indicative of a mixed-type inhibition mechanism Among 42 kinases tested BAMB-4 selectively inhibited ITPKA This compound serves as a valuable tool for studying ITPKA-mediated signaling in cellular models
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.