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Apexbio Technology LLC Bax channel blocker 335165-68-9 10mg
Supplier: Apexbio Technology LLC A445910
Bax channel blocker (CAS 335165-68-9) is a small molecule inhibitor targeting the Bax-mediated mitochondrial cytochrome c release pathway By modulating Bax channel activity this compound effectively suppresses the release of cytochrome c from mitochondria thereby interfering with the activation of apoptotic signaling cascades involving caspase 9 and downstream caspases In vitro studies report an IC50 of 0 52 M for the inhibition of Bax activity with substantial suppression of cytochrome c release observed at submicromolar levels Bax channel blocker serves as a valuable tool for investigating the mechanisms of mitochondrial apoptosis and for modulating apoptotic processes in experimental systems
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