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Medchemexpress LLC HY-13453 10mg Medchemexpress, BAY 11-7082 CAS:19542-67-7 Purity:>98%
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Supplier:  Medchemexpress LLC HY1345310MG

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Medchemexpress, HY-13453 10mg BAY 11-7082 CAS:19542-67-7 BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells[2][3][4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-202-8997


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