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Apexbio Technology LLC Bay 11-7085(Synonyms: BAY-11-7085, BAY 117085, BAY117085, Bay11-7085, BAY 11 7085, BAY-117085, Bay 11 7085), 10mM (in 1mL DMSO), CAS: 196309-76-9.
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Supplier:  Apexbio Technology LLC B30335.1

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Bay 11-7085 (CAS 196309-76-9) is a soluble inhibitor of nuclear factor-kappa B (NF- B) activation It inhibits cell proliferation and promotes apoptosis in various cell types through interference with NF- B signaling pathways Studies have demonstrated that Bay 11-7085 decreases DNA synthesis in endometriotic stromal cells (ECSCs) leading to cell cycle arrest at G0/G1 phase Furthermore treatment with Bay 11-7085 induces apoptosis by downregulating anti-apoptotic proteins such as Bcl-2 and Bcl-XL while enhancing activation of caspase-3 caspase-8 and caspase-9 Bay 11-7085 is commonly employed as a chemical probe in biomedical research on inflammation and apoptosis pathways

Catalog No. 50-000-60566


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