Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502940365

Cayman Chemical BAY-1125976, Purity: ≥98%, CAS: 1402608-02-9, 25 mg
SDP

Catalog No. 502940365
Encompass_Preferred

An allosteric inhibitor of Akt1 and -2 (IC50s = 5.2 and 18 nM, respectively, in a time-resolved FRET assay); selective for Akt1 and -2 over Akt3 (IC50 = 427 nM in the same assay) but does inhibit the activity of FLT1, -3, -4, and Mer by >50% in a panel of 227 kinases at 1 µM; inhibits the proliferation of 23 cancer cell lines (IC50s = 0.02-10 µM) and reduces tumor growth in KPL-4, MCF-7, and PDX mouse xenograft models at 50 mg/kg per day

Catalog No. 50-294-0365 Supplier Cayman Chemical Supplier No. 2891325 MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

An allosteric inhibitor of Akt1 and -2 (IC50s = 5.2 and 18 nM, respectively, in a time-resolved FRET assay); selective for Akt1 and -2 over Akt3 (IC50 = 427 nM in the same assay) but does inhibit the activity of FLT1, -3, -4, and Mer by >50% in a panel of 227 kinases at 1 µM; inhibits the proliferation of 23 cancer cell lines (IC50s = 0.02-10 µM) and reduces tumor growth in KPL-4, MCF-7, and PDX mouse xenograft models at 50 mg/kg per day

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.