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Selleck Chemical LLC BAY 1251152 CDK9 INHIBITOR 2MG
Supplier: Selleck Chemical LLC S87302MG
BAY1251152 is a potent PTEFb/CDK9 inhibitor with an IC50 value of 3 nM for CDK9 and an at least 50-fold selectivity against other CDKs in enzymatic assays. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins.Purity 98%, *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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