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Selleck Chemical LLC BAY 1436032
Supplier: Selleck Chemical LLC S85302MG
BAY-1436032 is a highly selective potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants
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