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Medchemexpress LLC BAY-593 | 2413020-56-9 | 99.9% | 476.53 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY16157350MG

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BAY-593 is an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity. It is for research use only.

  • Orally active GGTase-I inhibitor.
  • Blocks YAP1/TAZ signaling in animals.
  • Possesses antitumor activity.
  • Inhibits the proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively, in vitro.
  • Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple-negative breast cancer xenotransplantation mouse models in vivo.

Catalog No. 50-003-95320


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