Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.39% | C22H26ClN3O4 | 2 MG

Supplier:  Medchemexpress LLC HY509482MG

Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, intended for research use only. In vitro studies have shown that delivery of Bay 65-1942 prior to ischemia significantly decreased left ventricular infarct size and attenuated CK-MB levels compared with vehicle-treated animals. In vivo experiments demonstrated that Bay 65-1942, at a concentration of 10 μM, can synergistically inhibit cell viability and activate caspase 3/7 when combined with AZD6244 in MYL-R cells. For optimal preservation, store the solid form at 4°C in sealed conditions, away from moisture. When in solvent, store at -80°C for up to 6 months, or at -20°C for 1 month, also in sealed conditions away from moisture.

• ATP-competitive and selective IKKβ inhibitor.
• Decreases left ventricular infarct size and attenuates CK-MB levels in vitro.
• Synergistically inhibits cell viability and activates caspase 3/7 in vivo when combined with AZD6244.

Catalog No. 50-003-58150