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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 100 MG
Supplier: Medchemexpress LLC HY50948100MG
Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor. This compound is intended for research use only. In vitro studies show that delivery of Bay 65-1942 prior to ischemia significantly decreases left ventricular infarct size. In vivo, it demonstrates synergistic inhibition of cell viability and induces caspase 3/7 activation when combined with AZD6244 in MYL-R cells.
- Acts as an ATP-competitive and selective IKKβ inhibitor
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vivo
- Demonstrates synergistic inhibition of cell viability with AZD6244
- Induces caspase 3/7 activation with AZD6244
- Suitable for research applications
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