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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 25 MG

Supplier: Medchemexpress LLC 25MGHY50948
Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, appearing as a white to off-white solid. It has demonstrated efficacy in reducing left ventricular infarct size and attenuating CK-MB levels in vitro. In vivo studies show synergistic inhibition of cell viability when combined with AZD6244, and it induces caspase 3/7 activation, making it a valuable tool for research in cancer, inflammation, and immune system diseases.
- ATP-competitive and selective IKKβ inhibitor
- White to off-white solid appearance
- Soluble in DMSO (50 mg/mL) and H2O (2.17 mg/mL)
- Inhibits IKKβ activity
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vitro
- Demonstrates synergistic inhibition of cell viability with AZD6244 in vivo
- Induces caspase 3/7 activation in vivo
- Relevant for research in cancer, inflammation, and immune system diseases
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