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Cayman Chemical BAY 87-2243, Purity: ≥98%, CAS: 1227158-85-1, 10 mg
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Catalog No. 502941257
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A mitochondrial complex I inhibitor and inducer of ferroptosis; decreases ATP-dependent luciferase reporter activity and ATP levels in H1299luc cells; induces production of ROS, increases α-tocopherol-sensitive lipid peroxidation, and decreases GSH levels in SK-MEL-28 and G361 melanoma cells; reduces tumor weight, HIF-1α levels, and HIF-1α target gene expression in an H460 mouse xenograft model from 0.5-4 mg/kg; reduces tumor growth in the MEXF 276 and MEXF 1732 melanoma PDX mouse models

Catalog No. 50-294-1257 Supplier Cayman Chemical Supplier No. 2862610 MG
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A mitochondrial complex I inhibitor and inducer of ferroptosis; decreases ATP-dependent luciferase reporter activity and ATP levels in H1299luc cells; induces production of ROS, increases α-tocopherol-sensitive lipid peroxidation, and decreases GSH levels in SK-MEL-28 and G361 melanoma cells; reduces tumor weight, HIF-1α levels, and HIF-1α target gene expression in an H460 mouse xenograft model from 0.5-4 mg/kg; reduces tumor growth in the MEXF 276 and MEXF 1732 melanoma PDX mouse models

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