Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 100.0% | C32H38N2O5 | 25 MG
Supplier: Medchemexpress LLC 25MGHYA0036D
Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) with IC50s of 23 nM for ERα and 99 nM for ERβ. It is used for osteoporosis research and acts as an inhibitor of IL-6/GP130 protein-protein interactions, applicable for pancreatic cancer research.
- Oral, nonsteroidal selective estrogen receptor modulator
- IC50s of 23 nM for ERα and 99 nM for ERβ
- Small molecular GP130 inhibitor
- Inhibits STAT3 phosphorylation induced by IL-6 and IL-11
- Induces apoptosis in human pancreatic cancer cells
- Blocks STAT3 nuclear translocation induced by IL-6
- Inhibits cell migration in pancreatic cancer cells
- Inhibits tumor growth in a mouse model
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?