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Apexbio Technology LLC Bazedoxifene acetate 198481-33-3 25mg
Supplier: Apexbio Technology LLC A323325
Bazedoxifene acetate (CAS 198481-33-3) is a selective estrogen receptor modulator (SERM) targeting estrogen receptors (ER) It is designed to modulate ER activity thereby regulating estrogen-dependent cellular pathways Bazedoxifene acetate exerts its biological activity primarily through tissue-specific agonism and antagonism of ER In in vitro studies Bazedoxifene acetate demonstrates receptor modulation with reported affinities (Ki) of 26 nM for ER and 99 nM for ER Based on these pharmacological properties Bazedoxifene acetate holds research potential in osteoporosis and bone metabolism studies as well as in investigations of hormone-responsive cellular mechanisms and pancreatic cancer
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