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Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 25 MG
Supplier: Medchemexpress LLC 25MGHYA0036
Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) that acts as an inhibitor of IL-6/GP130 protein-protein interactions. It is used in research for osteoporosis and pancreatic cancer.
- Small molecular GP130 inhibitor
- Inhibits STAT3 phosphorylation induced by IL-6 and IL-11
- Induces apoptosis in human pancreatic cancer cells
- Inhibits STAT3 nuclear translocation induced by IL-6
- Blocks cell migration in pancreatic cancer cells by inhibiting GP130
- Inhibits Capan-1 tumor growth in mouse models
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