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Cayman Chemical BB-Cl-Amidine, 1802637-39-3, 1 mg
SDP

Supplier:  Cayman Chemical 170791

Encompass_Preferred

Molecular Formula C26H26ClN5O, Purity ≥95%, Formula Weight 460.0, Synonyms: N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-[1,1'-biphenyl]-4-carboxamide; A PAD inhibitor; a modified version of Cl-amidine; irreversibly inactivates all four PAD subtypes (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1 for PAD1-4, respectively); potency is increased 20-fold over that of Cl-amidine (EC50 = 8.8 M versus >200 M for Cl-amidine); longer half-life than Cl-amidine (1.75 h versus ~15 min, respectively); inhibits formation of neutrophil extracellular traps.

Catalog No. NC1103187


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