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Cayman Chemical BB-Cl-AmIdIntrIfluoroaceta 1mg
SDP

Supplier:  Cayman Chemical 170791 MG

Encompass_Preferred

A selective inhibitor of the B5i (LMP7) subunit of the immunoproteasome (IC50s 65 and 73 nM for mouse and human respectively) that demonstrates significantly weaker activity at the B5 subunit of the constitutive proteasome (IC50s 0.92 and 1.04 UM for mouse and human respectively) blocks the production of proinflammatory cytokines and inhibits TH1 and TH17 cell differentiation attenuates disease progression in several experimental models of autoimmune disorders as well as in some hematologic malignancies

Catalog No. 50-296-6731


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