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AdipoGen BCMA (human):Fc (human) (rec.) (50 µg)

Supplier: AdipoGen AG40B0080C050

Protein. The extracellular domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds human and mouse BAFF and APRIL. Purity: >95% (SDS-PAGE). BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK.
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