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Medchemexpress LLC BCR-ABL1-IN-1 | 1488090-21-6 | 99.8% | C18H12F3N3O2 | 25 MG
Supplier: Medchemexpress LLC 25MGHY145887
BCR-ABL1-IN-1 (Example 74) is an inhibitor for ABL1 (64-515) with an IC50 of 8.7 nM. It demonstrates antiproliferative activity against mouse BaF3 cells expressing BCR-ABL, showing a GI50 of 69 nM and an IC50 of 75 nM. Furthermore, BCR-ABL1-IN-1 inhibits the proliferation of Ba/F3-BCR-ABL1-WT cells with an IC50 of 30 nM. This compound can be utilized in research concerning diseases related to the central nervous system (CNS).
- Inhibitor for ABL1 (64-515) with an IC50 of 8.7 nM
- Shows antiproliferative activity against mouse BaF3 cells expressing BCR-ABL
- Inhibits proliferation of Ba/F3-BCR-ABL1-WT cells
- Suitable for research on diseases related to the central nervous system (CNS)
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