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Medchemexpress LLC BD-1047 dihydrobromide | 138356-21-5 | 98.45% | 437.04 | 1 ML

Supplier: Medchemexpress LLC HY16996A10MM/1ML
BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors. It attenuates Apomorphine-induced climbing and Phencyclidine-induced head twitches. It is for research use only and not sold to patients.
- Selective functional antagonist of sigma receptors.
- Attenuates Apomorphine-induced climbing.
- Attenuates Phencyclidine-induced head twitches.
- Prevents Cutamesine from reducing cell death induced by light exposure in murine photoreceptor-derived 661w cells.
- Attenuates Cutamesine from reducing mitochondrial damage and elevated caspase 3/7 activity.
- Decreases APO-induced climbing behavior at 10 mg/kg in mice.
- Counteracts the antidepressant-like effect induced by co-administration of pramipexole and sertraline.
- Reduces the increasing expression of pNR1 and reverses Sig-1 R agonists potentiated NMDA-induced pain behavior and pNR1 immunoreactivity.
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