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BD Annexin V: FITC Fluorescence Microscopy Kit

Fluorescence staining for apoptosis

Manufacturer:  BD 550911

Catalog No. BDB550911


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Includes: Annexin V-FITC, Annexin V Binding Buffer, and PBS Buffer

Description

Description

Early in apoptosis, before the loss of membrane integrity,phosphatidylserine (PS) translocates from the inner to outer leaflet of plasma membrane, exposing it to external cellular environment at surface of plasma membrane. Annexin V is 35-36kDa, calcium-dependent, phospholipid-binding protein with a high affinity for PS and is used to indirectly monitor PS translocation. Annexin V assay is facilitated by the observation that PS translocation appears to be a universal apoptotic phenomenon.

  • Binds to negatively charged phospholipid surfaces
  • Defined calcium and salt concentrations are required

Used in Fluorescence microscopy

Specifications

Specifications

Annexin V-FITC Fluorescence Microscopy Kit
Fluorescence microscopy
Annexin V-FITC, Annexin V binding buffer, and PBS buffer
25 Slides
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Research use only