BD Recombinant Soluble Human Fas

Catalog No.	Quantity
BDB554336	10 μg

Catalog No. BDB554336 Supplier BD Supplier No. 554336

Description

Expressed in the Baculovirus expression vector system and purified from insect cell lysate using an anti-Fas antibody, this protein lacks the transmembrane domain of the Fas receptor

Fas (APO-1, CD95) is an ∽42 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissue and cells including the thymus, liver, ovary and lung. FasL is a 40 kDa TNF family member membrane protein that induces apoptosis by binding to Fas, its cell-surface receptor. FasL is expressed on activated T and NK cells. Both Fas and FasL are thought to play an important role in the apoptotic processes that take place during T cell development. FasδTM has 63-base pair deletion starting at nucleotide sequence (700) GA TCC AGA and ending at nucleotide sequence GTT TGG G (762).FasδTM has a reduced molecular weight of ∽40 kDa.

• Alias: FasδTM
• Molecular weight: ∽40 kDa
• Storage buffer: Aqueous buffered solution containing BSA and glycerol
• Protein purity and integrity were verified by SDS-PAGE, and ELISA

Avoid multiple freeze-thaws of product.

Western blot, ELISA Standard, Functional assay

Specifications

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: Aqueous Buffered solution containing BSA and Glycerol
• Molecular Weight (g/mol): 42
• Name: Fas (Soluble) Recombinant Human Protein
• Preparation Method: Expressed in the Baculovirus expression vector system and purified from insect cell lysate using an anti-Fas Antibody
• Purification Method: ELISA, SDS-PAGE
• Quantity: 10 μg
• Storage Requirements: -80°C
• Recombinant: Recombinant
• Form: Solution

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

Research use only.