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Cayman Chemical Beclomethason 50mg

Supplier: Cayman Chemical 3319650 MG

An allosteric antagonist of PAR2 inhibits SLIGRL-induced calcium mobilization by wild-type and 10 mutant forms of PAR2 in a FLIPR assay (IC50s 23 and 12-780 nM respectively) selective for PAR2 over PAR4 and PAR1 (IC50s 50000 nM respectively in aBarrestin-2 recruitment assay) inhibits SLIGRL-induced phosphorylation of ERK in 1321N1 astrocytoma cells at 10 UM
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