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Medchemexpress LLC Benzamide, 4-butoxy-N-(2,4-difluorophenyl)- | 433967-28-3 | C17H17F2NO2 | 25 MG
Supplier: Medchemexpress LLC 25MGHY15393
VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. It is inactive or exhibits very weak antagonizing effects at other mGlu receptor subtypes.
- Highly selective mGlu5R allosteric modulator (PAM)
- EC50 of 33 nM
- Inactive or very weakly antagonizing at other mGlu receptor subtypes
- Enhances glutamate sensitivity of mGlu5
- Does not bind at the MPEP allosteric site of mGlu5
- Used for research purposes only
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