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Medchemexpress LLC Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxy-, 2,2,2-trifluoroacetate | 1336913-03-1 | 99.9% | 404.38 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY112217A

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PSEM 89S TFA is a selective and brain penetrant agonist for ion channels, orthogonally selective for Q79G and L141F. It is intended for research use only.

  • Activates layer 2/3 cortical neurons expressing PSAML141F,Y115F-5HT3 high conductance.
  • Reversibly silences transfected neurons by reducing cellular input resistance.
  • Reduces photostimulation-evoked feeding in mice with PSAML141F,Y115F-glycine receptor.
  • Demonstrates good brain penetrance in mice after intraperitoneal administration.
  • Suppresses fos in ChR2-expressing neurons in Agrp-cre mice.
  • Shows rapid rise in serum and brain, cleared within 1 hour in C57BL/6 mice.

Catalog No. 50-004-38811


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