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Apexbio Technology LLC 1,2,3,4,5,6-Hexabromocyclohexane(Synonyms: Hexabromocyclohexane, Benzene hexabromide, Hexabenzene bromide, HCH hexabromide), 10mM (in 1mL DMSO), CAS: 1837-91-8.
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Supplier:  Apexbio Technology LLC A45105.1

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1 2 3 4 5 6-Hexabromocyclohexane (CAS 1837-91-8) is a small molecule inhibitor targeting Janus kinase 2 (JAK2) It directly suppresses JAK2 tyrosine kinase activity by blocking ligand-induced autophosphorylation Experimental data indicate that treatment with 1 M of the compound for 16 hours decreases JAK2 autophosphorylation by approximately 50% whereas exposure to 50 M essentially abolishes kinase activity Notably it does not exhibit cytotoxicity at concentrations up to 100 M This compound serves as a valuable research tool for studying JAK2 signaling pathways and related cellular processes

Catalog No. 50-000-60963


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