Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000436103

Medchemexpress LLC Benzenemethanol,a,a-dimethyl-4-[(1Z)-2-[1-[4-(1-methylethoxy)phenyl]-1H-benzimidazol-5-yl]ethen | 1450929-77-7 | 99.1% | 412.52 | 50 MG
SDP

Catalog No. 5000436103
Encompass_Preferred

LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38. It has EC50s of <1 μM for Lassa, Machupo, and Junin viruses, and 1-10 μM for VSVg virus. It is a small-molecule viral entry inhibitor that targets the arenavirus envelope glycoprotein (GP).

  • Exhibits potent antiviral activity against a broad array of hemorrhagic fever arenaviruses.
  • Inhibits Lassa GP-pseudotyped lentivirus with an IC50 of 0.1-0.3 nM.
  • Protects mice from a lethal challenge with Tacaribe virus and dramatically reduces viral titers in plasma, spleen, and liver.
  • An increase in survival is also observed when the first dose is delayed by 1, 2, or 3 days after infection in mice.
  • Effective as a post-exposure therapeutic.

Catalog No. 50-004-36103 Supplier Medchemexpress LLC Supplier No. HY11276250MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38. It has EC50s of <1 μM for Lassa, Machupo, and Junin viruses, and 1-10 μM for VSVg virus. It is a small-molecule viral entry inhibitor that targets the arenavirus envelope glycoprotein (GP).

  • Exhibits potent antiviral activity against a broad array of hemorrhagic fever arenaviruses.
  • Inhibits Lassa GP-pseudotyped lentivirus with an IC50 of 0.1-0.3 nM.
  • Protects mice from a lethal challenge with Tacaribe virus and dramatically reduces viral titers in plasma, spleen, and liver.
  • An increase in survival is also observed when the first dose is delayed by 1, 2, or 3 days after infection in mice.
  • Effective as a post-exposure therapeutic.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.