Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000362670

Medchemexpress LLC Benzenepropanamide, a-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl)amino]-N-(2-furanylmethyl)-N-(2-thienylmethyl)- | 1681056-62-1 | 98.0% | 547.65 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY148113

Encompass_Preferred

PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor with an IC50 of 68 μM and a close structural analog of OSMI-1. In vitro studies show that PG34, at concentrations up to 50 μM for 24 hours, does not detectably inhibit OGT in CHO cells, nor does it affect apoptotic signaling. A moderate effect on cell viability was observed only at the highest concentration of 50 μM.

  • Weak O-GlcNAc transferase (OGT) inhibitor
  • IC50 of 68 μM
  • Structural analog of OSMI-1
  • Does not inhibit OGT in CHO cells (0.5-50 μM)
  • No effect on apoptotic signaling
  • Moderate effect on cell viability at 50 μM
  • No reduction in global O-GlcNAcylation (10, 25, 50 μM)

Catalog No. 50-003-62670


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.