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Medchemexpress LLC Benzenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]-, rel- | 2108567-79-7 | MFCD32690912 | 98.9% | C23H31N3O3S | 10MG
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Supplier:  Medchemexpress LLC HY139426A10MG

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(rel)-ML-SI3 is a small-molecule modulator of TRPML (mucolipin) ion channels used to probe TRPML1/2/3 function and autophagy in biochemical and cell-based research. It inhibits TRPML1 and TRPML3 while activating TRPML2, and is supplied at high purity for experimental use.

  • Modulates TRPML1, TRPML2, and TRPML3 activity in vitro.
  • Inhibits TRPML1 with IC50 ≈ 3.1 μM.
  • Activates TRPML2 with EC50 ≈ 3.3 μM.
  • Inhibits TRPML3 with IC50 ≈ 28.5 μM.
  • High purity suitable for biochemical and cellular assays.
  • Available as powder and as DMSO solution for screening.

Catalog No. 50-002-61089


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