Medchemexpress LLC Benzoic acid, 4-[[[3,5-bis(1,1-dimethylethyl)phenyl]methyl][2-[[(4-chlorophenyl)methyl] | 1834571-82-2 | 99.9% | 751.20 | C37H36ClF5N2O5S | 100MG

Supplier:  Medchemexpress LLC HY124500100MG

AC-4-130 is a small-molecule inhibitor that targets the STAT5 SH2 domain to block STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent transcription. It has demonstrated anti-cancer activity by inducing cell-cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells and is provided for research use in biochemical and cell-based assays.

• Selective STAT5 SH2 domain inhibitor.
• Disrupts STAT5 activation, dimerization, and nuclear translocation.
• Induces cell-cycle arrest and apoptosis in FLT3-ITD leukemia models.
• High purity, 99.9% (HPLC).
• Molecular weight 751.20; formula C37H36ClF5N2O5S.
• Available as solid (5 mg-100 mg) and 10 mM solution in DMSO.
• Supplied with batch-specific certificate of analysis.

Catalog No. 50-002-36433