Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000439664

Medchemexpress LLC Benzoic acid, 4-[5-(4,7-dimethyl-2-benzofuranyl)-1,2,4-oxadiazol-3-yl]- | 1952276-71-9 | 98.9% | 334.33 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11157350MG

Encompass_Preferred

KCL-286 (C286) is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist (EC50 = 1.9 nM). It activates RARβ2 in injured neurons, inducing axonal regeneration and modulating neuroinflammation and extracellular matrix molecules. It can also modulate the expression of chondroitin sulfate proteoglycans (CSPGs) by neuronal secretion of decorin, promoting myelination and aiding axonal growth.

  • Targets RARβ2 with selectivity over RAR α and RAR γ.
  • Activates RARβ2 in injured neurons.
  • Induces axonal regeneration of spinal and sensory nerves.
  • Modulates neuroinflammation and extracellular matrix molecules.
  • Promotes myelination and aids axonal growth.
  • Suitable for research in spinal cord injury and traumatic nerve injury.

Catalog No. 50-004-39664


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.