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Cayman Chemical Benzonatte 10mg
Supplier: Cayman Chemical 2393610 MG
A voltage-gated sodium channel blocker; blocks Nav1.7 currents in a concentration- and voltage-dependent manner (IC50s = 5.9 and 1.4 μM at holding potentials of -100 and -70 mV, respectively); blocks 80% of Nav1.3 currents in N1E-115 cells (100 μM); reduces the frequency of the cough reflex in anesthetized dogs
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