Apexbio Technology LLC Benzoquinonium dibromide 311-09-1 10mg

Supplier:  Apexbio Technology LLC B629710

Benzoquinonium dibromide is a small-molecule antagonist targeting nicotinic acetylcholine receptors (nAChRs) It is designed to inhibit neuronal acetylcholine receptor channel activity thereby regulating cholinergic neurotransmission Benzoquinonium dibromide exerts its biological activity primarily through blockade of nAChRs affecting the permeability of Na and K ions across neuronal membranes In in vitro studies using cultured fetal rat hippocampal neurons Benzoquinonium dibromide demonstrates dual effects at concentrations of 0 1 10 M it activates ion channel currents at conductance states of approximately 43 pS and 30 pS while also exhibiting channel-blocking activity at the open-channel state Based on these pharmacological properties Benzoquinonium dibromide holds research potential in neuropharmacology and neurophysiology for investigating cholinergic signaling pathways receptor activation mechanisms and receptor-channel interactions

Catalog No. 50-000-89802