Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate

Description

CAS: 501-53-1 | C8H7ClO2 | 170.592 g/mol

Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

Solubility
Miscible with ether, acetone and benzene.

Notes
Store in cool place. Moisture sensitive.

Specifications

Chemical Identifiers

• CAS: 501-53-1
• Molecular Formula: C8H7ClO2
• Molecular Weight (g/mol): 170.592
• MDL Number: MFCD00000640
• InChI Key: HSDAJNMJOMSNEV-UHFFFAOYSA-N
• Synonym: benzyl chloroformate, carbobenzoxy chloride, benzyl chlorocarbonate, cbz chloride, benzyloxycarbonyl chloride, carbobenzyloxy chloride, carbonochloridic acid, phenylmethyl ester, benzylcarbonyl chloride, cbz-cl, chloroformic acid, benzyl ester
• PubChem CID: 10387
• IUPAC Name: benzyl carbonochloridate
• SMILES: C1=CC=C(C=C1)COC(=O)Cl

• Melting Point: -20°C
• Density: 1.195
• Boiling Point: 178°C to 180°C
• Flash Point: 125°C (257°F)
• Odor: Acrid
• Refractive Index: 1.517
• Quantity: 250 g
• UN Number: UN1739
• Sensitivity: Moisture sensitive
• Merck Index: 14,1801
• Solubility Information: Miscible with ether,acetone and benzene.
• Formula Weight: 170.6
• Percent Purity: 95%
• Chemical Name or Material: Benzyl chloroformate, stabilized with ≈0.1% sodium carbonate

Safety and Handling

Hazard Category	H227-H290-H303-H314-H332-H335-H336-H350-H373
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P201-P202-P210-P234-P235-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P390-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: BENZYL CHLOROFORMATE
EINECSNumber	207-925-0
RTECSNumber	LQ5860000
TSCA	Yes
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only