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Medchemexpress LLC Berberine hemisulfate | 316-41-6 | 384.40 | 5 G
SDP

Supplier:  Medchemexpress LLC HYN0716A5G

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Berberine hemisulfate is the hemisulfate form of Berberine. It is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective, and neuroprotective activity.

  • Exhibits antimicrobial activity by inhibiting cell division protein FtsZ, or through DNA/RNA binding causing DNA/RNA damage.
  • Exhibits anti-inflammatory activity by inhibiting TNF-α and the activation of its downstream pathway AP-1 and NF-kB.
  • Exhibits neuroprotective efficacy by inhibiting reactive oxygen species (ROS) production and caspase activation, and activating the PI3K/Akt signaling pathway and heme oxygenase-1 (HO-1) expression.
  • Attenuates metabolic diseases through regulations of lipid composition and inhibition of insulin resistance.

Catalog No. 50-004-15890


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