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Medchemexpress LLC Berubicin (hydrochloride) | 293736-67-1 | 95.08% | 670.10 | 5 MG
Supplier: Medchemexpress LLC HY14942A5MG
Berubicin hydrochloride is a Doxorubicin analog capable of crossing the blood-brain barrier. It inhibits P-gp and MRP1-mediated efflux, suppressing glioblastoma multiforme (GBM). This compound exhibits toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells. It is suitable for studying nervous system-related tumors.
- Can cross the blood-brain barrier
- Inhibits P-gp and MRP1-mediated efflux
- Suppresses glioblastoma multiforme (GBM)
- Exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB)
- Induces apoptosis in neuroblastoma cells
- Useful in the study of nervous system-related tumors
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