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Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 1 MG
Supplier: Medchemexpress LLC HY1532261MG
BET-IN-14 is an orally active pan BET inhibitor (IC50: 5.35 nM) exhibiting anti-cancer activity. It shows anti-tumor effects against various cancer cell lines, including MM.1S, Ty-82, MV-4-11, and KG-1 cells, with an average IC50 of 174.7 nM after 72 hours. In vivo, BET-IN-14 inhibits tumor growth in MV-4-11 xenograft models.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- Effective against various cancer cell lines (MM.1S, Ty-82, MV-4-11, KG-1)
- Inhibits tumor growth in xenograft models
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