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Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 25 MG
SDP

Catalog No. 5000375622
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BET-IN-14 is an orally active pan BET inhibitor with an IC50 of 5.35 nM. It exhibits anti-cancer activity. In vitro studies show that BET-IN-14 (Compound 171) has anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM), particularly in MM.1S, Ty-82, MV-4-11, and KG-1 cells. In vivo, BET-IN-14 (50 and 100 mg/kg, p.o., qd) inhibits tumor growth in MV-4-11 xenograft models by 60.36%.

  • Orally active pan BET inhibitor with high potency (IC50 of 5.35 nM)
  • Displays anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM)
  • Effective in MM.1S, Ty-82, MV-4-11, and KG-1 cells
  • Inhibits tumor growth in MV-4-11 xenograft models by over 60% at tested dosages

Catalog No. 50-003-75622 Supplier Medchemexpress LLC Supplier No. 25MGHY153226
May include imposed supplier surcharges.
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BET-IN-14 is an orally active pan BET inhibitor with an IC50 of 5.35 nM. It exhibits anti-cancer activity. In vitro studies show that BET-IN-14 (Compound 171) has anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM), particularly in MM.1S, Ty-82, MV-4-11, and KG-1 cells. In vivo, BET-IN-14 (50 and 100 mg/kg, p.o., qd) inhibits tumor growth in MV-4-11 xenograft models by 60.36%.

  • Orally active pan BET inhibitor with high potency (IC50 of 5.35 nM)
  • Displays anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM)
  • Effective in MM.1S, Ty-82, MV-4-11, and KG-1 cells
  • Inhibits tumor growth in MV-4-11 xenograft models by over 60% at tested dosages

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