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CPC Scientific Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2 (trifluoroacetate salt) 0.5MG

Supplier: CPC Scientific AMYD028A
Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.ONE-LETTER SEQUENCE: Ac-NWCKRGRKQCKTHPH-NH2 (Cys and bridge)MOLECULAR FORMULA: C81H128N32O19S2MOLECULAR WEIGHT:1918.3STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [289634-54-4], SYNONYMS: Acetyl-Amyloid β/A4 Protein Precursor (96-110) (cyclized), Ac-APP (96-110) (cyclized)RESEARCH AREA: Alzheimer's DiseaseREFERENCES: D.H. Small et al., J. Neurosci., 14, 2117 (1994)
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