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Sigma Aldrich Fine Chemicals Biosciences beta Glucuronidase/Arylsul
Supplier: Sigma Aldrich Fine Chemicals Biosciences 10127698001
-Glucuronidase/Arylsulfatase from Helix pomatiais is the most widely used enzyme preparation containing sulfatase activity and has a very broad specificity. It is a crude mixture of enzymes and the preparation does not involve any kind of chromatographic separation. This preparation contains both glucuronidase and sulfatase activity. Enzymatic hydrolysis prior to detection is essential for achieving high sensitivity during analysis. After hydrolysis the sample may be analyzed by mass spectroscopy gas chromatography HPLC or immunoassays. for doping analysis the sulfatase activity in addition to the glucuronidase activity is essential for the detection of all drug conjugates present in the sample. -Glucuronidase/Arylsulfatase is also used for the enzymatic hydrolysis of glucuronides and sulfate esters in biological fluids and primarily urine.
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