Apexbio Technology LLC Betamethasone 378-44-9 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC B18965.1

Betamethasone is a synthetic corticosteroid functioning primarily as a glucocorticoid receptor agonist Mechanistically it modulates gene expression through binding glucocorticoid receptors regulating transcription factors and subsequently affecting protein synthesis Betamethasone influences inflammatory pathways by inhibiting key enzyme expressions such as phospholipase A2 cyclooxygenase-2 (COX-2) and nitric oxide synthase (NOS) resulting in decreased synthesis of inflammatory mediators like prostaglandins leukotrienes and nitric oxide Additionally it has been reported to suppress keratinocyte proliferation Due to its glucocorticoid-modulating properties and anti-inflammatory effects betamethasone is commonly employed in biomedical research involving inflammatory signaling pathways dermatological models and gene expression studies

Catalog No. 50-000-63766