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Enzo Life Sciences Betulinic acid (high purity) (25mg). CAS: 472-15-1
SDP

Supplier:  Enzo Life Sciences ALX350277M025

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Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Triggers CD95- and p53-independent apoptosis via activation of caspases. It induces mitochondrial permeability pore opening and the release of cytochrome c and apoptosis-inducing factor. Displays anti-HIV activity. EC50 for inhibion of HIV-1 replicaton in H9 lymphocytes: 1.4µM. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥97% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: +4°C.

Catalog No. 50-200-8823


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