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Selleck Chemical LLC Dactolisib (BEZ235) 50mg 915019-65-7 NVP-BEZ235

Supplier: Selleck Chemical LLC S100950MG

Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for¿p110?/?/?/?¿and mTOR(p70S6K)¿with¿IC50¿of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits¿ATR¿with¿IC50¿of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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