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Medchemexpress LLC bFGF (119-126) | 152051-61-1 | 99.93% | 993.16 | 10 MG
Supplier: Medchemexpress LLC HYP532110MG
bFGF (119-126) is a ligand of basic fibroblast growth factor (bFGF) that inhibits its interaction with fibroblast growth factor receptor 1 (FGFR1). This suppresses FGFR1 phosphorylation and downstream signaling, leading to cell apoptosis and inhibition of proliferation, migration, angiogenesis, and metastasis. It can enhance cellular uptake when conjugated with a carrier and has shown enhanced tumor inhibitory effects in combination with ultrasound and Doxorubicin, useful in various cancer research.
- Enhances cellular uptake via FGFR-mediated endocytosis when conjugated with a carrier
- Effective FGFR-targeted ligand
- Enhances tumor inhibitory effects when combined with ultrasound and Doxorubicin
- Applicable for research in lung, breast, glioblastoma, and ovarian cancers.
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