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Cayman Chemical BGJ398phosphate 10mg
Supplier: Cayman Chemical 3929210 MG
A pan FGFR inhibitor (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); suppresses proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively); inhibited tumor growth in an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3 at 10-30 mg/kg
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